第一军医大学学报2001，Vol.21Issue(1)：40-41,2.
急性白血病患者病情与D-二聚体含量相关性的研究
Study on correlation of disease status with D-dimmer level in acute leukemia patients
易正山 1陈琪 1周淑芸 1林榕 1徐小兰 1杨艺1
作者信息
摘要
Abstract
Objective To investigate the correlation of plasma D-dimmerlevels with the status of acute leukemia and explore its clinical significance. Methods Five hundred bone marrow nucleated cells from patients with acute non-lymphoblastic leukemia (ANLL)and acute lymphoblastic leukemia (ALL) were isolated by routine microscopic counting. The plasma prothrombin time/international normalized ratio (PT/INR) and activated partial thromboplastin time (APTT) of the cells were measured by one-stage clotting method in a coagulation instrument. The content of D-dimmer was determined by latex agglutination assay. Results The total number of primary and naive cells was positively correlated with the PT/INR and D-dimmer level in both ANLL and ALL group,but the plasma PT/INR levels were largely within normal range with only a few exceptions. High abnormality rate of D-dimmer levels, however, was observed in paralleled with the total number primary and naive cells. Conclusion The variation of D-dimmer level can be the one of the index as to judge the disease status.关键词
白血病/二聚体分类
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易正山,陈琪,周淑芸,林榕,徐小兰,杨艺..急性白血病患者病情与D-二聚体含量相关性的研究[J].第一军医大学学报,2001,21(1):40-41,2.
