中国现代医学杂志2004，Vol.14Issue(8)：42-44,3.
50例高血压患者内皮素和一氧化氮与血压节律相关性的研究
Endothelin, nitric oxide and blood pressure rhythm in 50 patients with essential hypertension
彭永权 1刘应才 1彭博文1
作者信息
- 1. 四川省泸州医学院附属医院,心内科,四川,646000
- 折叠
摘要
Abstract
Objective:To evaluate relationship between endothelin, nitric oxide and ciradian rhythm of blood pressure in essential hypertension. Methods :50 Patients with essential hypertensitn and 25 patients with normotension were monitored 24 hour blood pressure and examined endothelin , mitric oxide. Results:In hypertension group, ET increased and NO decreased: According to results of the monitoring, 50 patients hypertension were divided dipper hy pertension and non - dipper hypertension. In non - dippers, endothelin was significantly higher (54.2 ± 18.9) VS (37.7 ± 10.1) ng/L,nitric oxide was lower (32.9 ± 12.8) VS (48.7 ± 11.2) mg/L. There were significant negative correlation between nocturnal blood pressure fall and endothelin (r = -0.51, P ＜ 0.05 ), positive correcation between noctural blood pressure fall and nitric oxide) ( r = 0.53, P ＜ 0.05 ). Conclusions: Endothelin and nitric oxide might have effects in circadian rhythm of blood pressure in essential hypertension.关键词
高血压/内皮素/一氧化氮/血压节律Key words
essential hypertonsion/endothelin/nitric oxide/blood pressure rhythm分类
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彭永权,刘应才,彭博文..50例高血压患者内皮素和一氧化氮与血压节律相关性的研究[J].中国现代医学杂志,2004,14(8):42-44,3.
