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无支架四叶牛心包二尖瓣交界缝合缘宽度设计的实验研究

胡野荣 陈晓凤 龚光甫 刘文亮 吴忠仕

中国现代医学杂志2003,Vol.13Issue(22):42-44,3.
中国现代医学杂志2003,Vol.13Issue(22):42-44,3.

无支架四叶牛心包二尖瓣交界缝合缘宽度设计的实验研究

Investigation on width of commissure suture of stentless quadrileaflet bovine pericardial mitral valve

胡野荣 1陈晓凤 1龚光甫 1刘文亮 1吴忠仕1

作者信息

  • 1. 中南大学湘雅二医院胸心外科,长沙,410011
  • 折叠

摘要

Abstract

Objective:To investigate the suitable width of commissure suture of the stentless quadrileaflet bovine pericardial mitral valve (CS valve) in terms of biomechanical properties.Methods:Bovine pericardium strips tanned with glutaraldehyde were measured with thickness and cut off in the middle, then sewn up according to different distances from the sewing point to the cutting rim. The absolute load ,failure tensile stress and failure strain of strips were measured through uniaxial load testing. According to different suture width , the strips were divided into four groups: 1mm width group, 2mm width group, 3mm width group and 4mm width group.Results:In 2mm, 3mm and 4mm groups, the absolute loads were (10.56±1.95)N、(13.57±3.27)N and (15.71±3.86)N, failure tensile stresses were (6.88±1.29)MPa,(8.25±2.58)MPa and (8.94±2.05) MPa and failure strains were(29.95±4.11)%,(33.31±5.02)% and (33.07±3.73)%.They were all significantly higher than those in 1mm group which were (7.05±1.40)N,(4.62±1.08) MPa and (24.11±4.40)% respectively (P≤0.01).The absolute loads in 3mm group and 4mm group and the failure tensile stress in 4mm group were also higher than in 2mm group(P≤0.05).Other data showed no significant difference in all the groups.Conclusions:The width of commissure suture of the stentless quadrileaflet bovine pericardial mitral valve(CS valve) should be at least larger than 1mm according to its biomechanical properties. Generally its suitable width is 2mm.

关键词

生物力学特性/牛心包/生物瓣/交界缝合缘宽度

Key words

Biomechanical properties/Bovine pericardium/Bioprosthetic calve/Commissure suture width

分类

医药卫生

引用本文复制引用

胡野荣,陈晓凤,龚光甫,刘文亮,吴忠仕..无支架四叶牛心包二尖瓣交界缝合缘宽度设计的实验研究[J].中国现代医学杂志,2003,13(22):42-44,3.

中国现代医学杂志

OACSTPCD

1005-8982

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