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几种胶原酶抑制剂滴眼液的效果比较

沈远萍 张泺 胡正

眼科新进展2000,Vol.20Issue(6):426-427,2.
眼科新进展2000,Vol.20Issue(6):426-427,2.

几种胶原酶抑制剂滴眼液的效果比较

Comparative study on the effects of collagenase inhibitor in different eye drops

沈远萍 1张泺 1胡正1

作者信息

  • 1. 同济医科大学附属同济医院眼科湖北省武汉市,430030
  • 折叠

摘要

Abstract

Objective To investigate, compare and filtrate the collagenase inhibitor effects among six kinds of eye drops for clinical use.Methods The collagenase inhibitor’s effects were detected by rat's collagen and collagenase with comassie brilliant blue colorimetric method.Results The inhibitting collagenase effects among six kinds of eye drops were different: the effect of cartopril was the strongest;the acetylcysteine and sodium edetate were more strong and the sodium citrate, sodium hyposulfite and tetracycline were less strong.Conclusion  0.5g*L-1cartopril eye drops has stronger efficacy to inhibit collagenase, with less side effect or stimulation,more convenient resource and preparation than other eye drops.

关键词

胶原酶/胶原酶抑制剂/考马斯亮蓝比色法/卡托普利

Key words

collagenase/collagenase inhibitor/comassie brilliant blue colorimetric method/cartopril

分类

医药卫生

引用本文复制引用

沈远萍,张泺,胡正..几种胶原酶抑制剂滴眼液的效果比较[J].眼科新进展,2000,20(6):426-427,2.

眼科新进展

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