西安医科大学学报2000，Vol.21Issue(5)：431-432,2.
血清IV型胶原在肝纤维化诊断中的意义
Diagnostic value of serum type IV collagen in hepatic fibrosis
李小维 1苌新明1
作者信息
- 1. 广州医学院第二附属医院，广州 510260
- 折叠
摘要
Abstract
Objective To study the diagnostic value of serum type IV collagen(IV-C) in hepatic fibrosis. Methods Serum IV-C levels were detected by using radioimmunoassay(RIA) and were compared with serum type Ⅲ procollagen(PCⅢ ) levels in normal controls(NC) and patients with chronic liver diseases. Results Serum IV-C and PCⅢ levels in patients with chronic liver diseases were all much higher than those in NC(P < 0.01, totally). Serum IV-C level in severe chronic hepa titis(CH) group was significantly higher than those in mild and median CH groups (P<0.01 total ly), and that in active liver cirrhosis(LC) group was significantly higher than that in static LC group (P＜0.05). There were significant positive correlation between serum IV-C level and serum PcⅢ level both in CH group and in LC group ( in CH γ=0.7023, in LC γ=0. 5878, P＜0. 001).Conclusion Serum IV-C level could reflect the activity of hepatic fibrogenesis.关键词
肝纤维化/IV型胶原/慢性肝病/肝硬变Key words
hepatic fibrosis/type IV collagen/chronic hepatitis/liver cirrhosis分类
医药卫生引用本文复制引用
李小维,苌新明..血清IV型胶原在肝纤维化诊断中的意义[J].西安医科大学学报,2000,21(5):431-432,2.
