中国现代医学杂志2001，Vol.11Issue(3)：43-44,46,3.
HA/FDFB修复兔胫骨缺损的实验研究
REPAIRING TIBIA DEFECIS BY HYDROXYLAPATITE COMBINED WITH FREEZED-DRIED FETAL BONE
黄洪章 1中山医科大学孙逸仙纪念医院口腔颌面外科 1段昌华2
作者信息
- 1. 中山医科大学孙逸仙纪念医院口腔颌面外科
- 2. 广东省江门市口腔医院
- 折叠
摘要
Abstract
Objective: To evaluate the osteogenetic activity of hydroxylapatite combined with freezed-dried fetal bone (HA/FDFB). Methods:Biolateral tibia defects were created in sixten adult rabbits. Left defects were filled with HA alone, and the right defects were filled with HA/FDFB. Animals were sacrified at 1. 4.12 and 24 weeks postoperation. The tibia specimen were assessed byradiograph and light macroscopy.Results: No bone formation was o bserved except for a few section gathered from the lates stage in theleft defects. Most part of space between the HA particles was filled with fibrous connective tissue during the experiment. However, alittle new bone had formed at 4 weeks postoperation in the right defects. 12 weeks later, woven bone penetratedalmost the wholeblock of HA. The newly formed bone completely filled the space of the rnass of HA and showed a lamella bone appearance at 24 weekspostoperation. Conclusions: This study indicated at that HA combined with FDFB showed a highly osteogenetic activtiy and could playa role in promoting bone repairing关键词
羟基磷灰石/冻干异体骨/胚胎骨/骨修复分类
医药卫生引用本文复制引用
黄洪章,中山医科大学孙逸仙纪念医院口腔颌面外科,段昌华..HA/FDFB修复兔胫骨缺损的实验研究[J].中国现代医学杂志,2001,11(3):43-44,46,3.
