中国中西医结合杂志2001，Vol.21Issue(1)：43-46,4.
黄芪当归对急性缺血再灌注大鼠肾损伤的治疗作用
Therapeutic Effect of Astragalus and Angelica on Renal Injury Induced by Ischemia/Reperfusion in Rats
摘要
Abstract
Objective: To observe the effect of Astragalus and Angelica onacute renal injury. Methods: Using the ischemia/reperfusion model established by blocking blood flow through clamping of bilateral renal artery for 45 min, the changes of glomerular filtration rate (GFR), renal plasma flow (RPF), fractional excretion of sodium (FENa), urinary volume (UV) and mean arterial pressure (MAP) as well as the morphological change of kidney before and after ischemia/reperfusion were observed. Results: Astragalus and Angelica could promote recovery of RPF and GFR after ischemia/reperfusion, prevent the oliguria or shorten the oliguria period, reduce the increment of FENa and improve the histomorphological injury of kidney. Conclusion: Astragalus and Angelica have certain effect in protecting kidney from acute renal injury.关键词
黄芪/当归/缺血再灌注/肾功能分类
医药卫生引用本文复制引用
盛梅笑,李惊子,王海燕,屈磊,许远,邹万忠,洪健美..黄芪当归对急性缺血再灌注大鼠肾损伤的治疗作用[J].中国中西医结合杂志,2001,21(1):43-46,4.基金项目
国家自然科学基金资助课题(No.39970929) （No.39970929）
