河南医科大学学报2000，Vol.35Issue(5)：443-444,2.
双氯芬酸胆碱的研制
Synthesis of diclofenac acid-choline
刘利娥 1阎素清 1刘洁 1张幼梅2
作者信息
- 1. 河南医科大学卫生化学教研室郑州 450052
- 2. 河南医科大学第一附属医院眼科郑州 450052
- 折叠
摘要
Abstract
Aim: To reduce the stimulation of diclofenac sodium, a new diclofenac acid salt was prepared. Methodls: The di-clofenac acid-chohne was manufactured by reacting diclofenac acid with chohne at the tempemmre of 50℃ for some time . Fe-sults: The productivity of the product was more than 75.2% (purity above 99.7% ). The product, with a molecular formula of C19H24O3N2C12, was identified on the basis of spectral data (UV、IR、1HNMR、13CNMR and MS). Conclusion: Its synthetic line hashigh yield with less industrial pollution.关键词
双氯芬酸胆碱/合成/分析Key words
diclofenac acid-chohne/synthesis/analysis引用本文复制引用
刘利娥,阎素清,刘洁,张幼梅..双氯芬酸胆碱的研制[J].河南医科大学学报,2000,35(5):443-444,2.
