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大鼠大脑内血管的氮能神经支配

薛爽 陈子馨

解剖学杂志2000,Vol.23Issue(5):443-446,4.
解剖学杂志2000,Vol.23Issue(5):443-446,4.

大鼠大脑内血管的氮能神经支配

NITERGIC INNERVATION OF THE CEREBROVASCULATURE IN THE RAT BRAIN

薛爽 1陈子馨1

作者信息

  • 1. 中日友好医院神经科,北京 100029
  • 折叠

摘要

Abstract

Objective: To observe the nitergic innervation of blood vessels and nitergic neuron in the ratbrain, and further prove the effect of nitric oxide in the blood vessels. Methods: Brain were removed from 5 Wistar rats by perfusion fixation. Sections were cut by a freezing-microtome, freefloating sections were stained for NADPH-d histochemical method. Results: Nitergic neuronswere detected in the rat brain, 2 types could be readily distinguished: bipolar neurons and mutipolar neurons. Their fine branching dendrities closely connected blood vessels. We found fineperivascular fibers of varicose NADPH-d positive fibers plexus also in closely associated with microvessels. Conclusion: NADPH-d positive neurons scatter and their fine dendrites is closely associated with blood vessels. This provide anatomical basis for the innervation of the vessels by nitrergic nerve fibers, suggesting that NO involves in regulation of vascular tone of the brain bloodvessels and cerebral circulation.

关键词

大鼠//血管/一氧化氮/组织化学

Key words

brain/blood vessel/nitric oxide/histochemistry

分类

医药卫生

引用本文复制引用

薛爽,陈子馨..大鼠大脑内血管的氮能神经支配[J].解剖学杂志,2000,23(5):443-446,4.

解剖学杂志

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