国际眼科杂志2008，Vol.8Issue(3)：445-447,3.
兔眼滤过性手术中植入硅凝胶膜的实验研究
Experimental study of silicone membrane implanted beneath the scleral flap during filtering surgery in rabbits
裴澄 1孙乃学 2韩真 3吕莎莎1
作者信息
- 1. 710061,中国陕西省西安市,西安交通大学医学院第一附属医院眼科
- 2. 710004,中国陕西省西安市,西安交通大学医学院第二附属医院眼科
- 3. 721001,中国陕西省宝鸡市,宝鸡市中医院眼科
- 折叠
摘要
Abstract
·AIM: To investigate the efficacy and security of the silicone membrane implant through observing intraocular pressure, filtering blebs and histopathologic results.·METHODS; Forty rabbits were randomly divided into 4 groups. Each group consisted of 10 rabbits. Trabecu-lectomy and silicone membrane implantation were performed in one eye of each rabbit, while the other eye was only performed trabeculectomy as control. The change of intraocular pressure, filtering blebs were observed postoperatively. And each eye had undergone histopathologic examination.·RESULTS:The duration of low intraocular pressure and existence of filtering blebs in implanted eyes was longer than that in controlled eyes. Light microscopy revealed that patent drainage tract and biting site could be seen in silicone membrane implanted eye. The activity and regularity of fibroblast proliferation in implanted eyes and controlled eyes were similar. Excessive expression of fibroblast proliferation was not induced by silicone membrane.·CONCLUSION: Characterized by safety, effectiveness and simplicity, silicone membrane implantation can act as a new drainage surgery.KEYWORDS: silicone membrane; drainage surgery;intraocular pressure关键词
硅凝胶膜/引流术/眼内压Key words
silicone membrane/drainage surgery/intraocular pressure分类
医药卫生引用本文复制引用
裴澄,孙乃学,韩真,吕莎莎..兔眼滤过性手术中植入硅凝胶膜的实验研究[J].国际眼科杂志,2008,8(3):445-447,3.
