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变应性鼻炎吸入性变应原特异性IgE检测分析

杨钦泰 黄雪琨 陈玉莲 张革化 李源

中山大学学报(医学科学版)2009,Vol.30Issue(4):446-449,4.
中山大学学报(医学科学版)2009,Vol.30Issue(4):446-449,4.

变应性鼻炎吸入性变应原特异性IgE检测分析

Aeroallergen Specific IgE in Serum of Patients with Allergic Rhinitis

杨钦泰 1黄雪琨 1陈玉莲 1张革化 1李源1

作者信息

  • 1. 中山大学附属第三医院耳鼻咽喉-头颈外科,广东,广州,510630
  • 折叠

摘要

Abstract

[Objective] To study the aeroallergens in the patients with allergic rhinitis in Guangzhou.[Methods] Using the German screen allergens quantitative detection system to determinate serum aeroallergen specific IgE and total IgE levels of 625 cases with allergic rhinitis diagnosed in The Third Hospital of SUN Yat-sen University.The samples were stratified on two age groups:the juvenile and the adult.Difference of serum aeroallergen specific IgE of the two groups was investigated.[Results]Aeroallergen specific IgE antibody in the serum of 625 patients with allergic rhinitis were positive.Total IgE in serum was positive in 413 cases,accounting for 66.1%.The positive rate of total IgE was less than that of aeroallergen specific IgE.The positive rate of aeroallergen specific IgE in order were mite mixture (84.32%),cockroach (19.04%),cypress (15.20%),cat-dog epithelia (13.12%),tree mixture (7.20%),ragweed (5.12%),humulus lupulus (1.76%),mugwort (1.76%),mould mixture (1.44%).In the two groups,the positive rate of aeroallergen specific IgE in order were similar.There were significantly higher sensitivity and positive rate of mite mixture in the juvenile group than the adult group (P < 0.01).[Conclusion] The most important aeroallergens are mite mixture,cockroach,cypress,cat-dog epithelia,which could be referenced as Guangzhou patients .The juvenile is more sensitive to mite than the adult.

关键词

变应性鼻炎/变应原/特异性免疫球蛋白E

Key words

allergic rhinitis/allergen/specific IgE

分类

医药卫生

引用本文复制引用

杨钦泰,黄雪琨,陈玉莲,张革化,李源..变应性鼻炎吸入性变应原特异性IgE检测分析[J].中山大学学报(医学科学版),2009,30(4):446-449,4.

基金项目

广东省医学科研基金(B2008051) (B2008051)

中山大学学报(医学科学版)

OA北大核心CSCDCSTPCD

1672-3554

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