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The effects on surgery and preoperative patients with non-small cell lung cancer by preoperative bronchial artery infusion chemotherapy

Shuhong Tang Jilai Bian Mingwu Li

中德临床肿瘤学杂志(英文版)2008,Vol.7Issue(8):447-450,4.
中德临床肿瘤学杂志(英文版)2008,Vol.7Issue(8):447-450,4.

The effects on surgery and preoperative patients with non-small cell lung cancer by preoperative bronchial artery infusion chemotherapy

The effects on surgery and preoperative patients with non-small cell lung cancer by preoperative bronchial artery infusion chemotherapy

Shuhong Tang 1Jilai Bian 1Mingwu Li1

作者信息

  • 1. Department of Oncology, The No.5 People's Hospital, Dalian 116021, China
  • 折叠

摘要

Abstract

Objective: To study the efficiency, safety and feasibility of preoperative bronchial artery infusion (BAI) chemotherapy on operation in patients with locally advanced (stage Ⅲ) non-small cell lung cancer (NSCLC).Methods: 92 cases with locally advanced NSCLC patients were randomly divided into two groups: (1) BAI chemotherapy group: 39 cases were received BAI chemotherapy for 2 courses and followed surgery; (2) surgery alone group: 51 cases were treated by operation alone.The complete resection rate and preoperative complications were compared between these two groups.Results: In BAI chemotherapy group, the rate of clinical efficiency was 68.3% with slight toxicity.In BAI chemotherapy group the surgery complete resection rate was 89.7%, which was significantly higher than that in surgery alone group (72.5%, P<0.05).No significant differences of blood loss, operative complications and mortality were observed between these two groups.Conclusion: BAI neoadjuvant chemotherapy was safe and effective, which can increase the complete resection rate of the tumor and did not increase the operative complications and mortality.

关键词

non-small cell lung cancer (NSCLC)/neoadjuvant chemotherapy/bronchial artery infusion (BAI)/surgery

Key words

non-small cell lung cancer (NSCLC)/neoadjuvant chemotherapy/bronchial artery infusion (BAI)/surgery

分类

医药卫生

引用本文复制引用

Shuhong Tang,Jilai Bian,Mingwu Li..The effects on surgery and preoperative patients with non-small cell lung cancer by preoperative bronchial artery infusion chemotherapy[J].中德临床肿瘤学杂志(英文版),2008,7(8):447-450,4.

基金项目

Supported by a grant from the Foundation of Science and Technology of Dalian (No.20039907). (No.20039907)

中德临床肿瘤学杂志(英文版)

OACSTPCD

2095-9621

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