首页|期刊导航|中德临床肿瘤学杂志(英文版)|The effects on surgery and preoperative patients with non-small cell lung cancer by preoperative bronchial artery infusion chemotherapy
中德临床肿瘤学杂志(英文版)2008,Vol.7Issue(8):447-450,4.
The effects on surgery and preoperative patients with non-small cell lung cancer by preoperative bronchial artery infusion chemotherapy
The effects on surgery and preoperative patients with non-small cell lung cancer by preoperative bronchial artery infusion chemotherapy
摘要
Abstract
Objective: To study the efficiency, safety and feasibility of preoperative bronchial artery infusion (BAI) chemotherapy on operation in patients with locally advanced (stage Ⅲ) non-small cell lung cancer (NSCLC).Methods: 92 cases with locally advanced NSCLC patients were randomly divided into two groups: (1) BAI chemotherapy group: 39 cases were received BAI chemotherapy for 2 courses and followed surgery; (2) surgery alone group: 51 cases were treated by operation alone.The complete resection rate and preoperative complications were compared between these two groups.Results: In BAI chemotherapy group, the rate of clinical efficiency was 68.3% with slight toxicity.In BAI chemotherapy group the surgery complete resection rate was 89.7%, which was significantly higher than that in surgery alone group (72.5%, P<0.05).No significant differences of blood loss, operative complications and mortality were observed between these two groups.Conclusion: BAI neoadjuvant chemotherapy was safe and effective, which can increase the complete resection rate of the tumor and did not increase the operative complications and mortality.关键词
non-small cell lung cancer (NSCLC)/neoadjuvant chemotherapy/bronchial artery infusion (BAI)/surgeryKey words
non-small cell lung cancer (NSCLC)/neoadjuvant chemotherapy/bronchial artery infusion (BAI)/surgery分类
医药卫生引用本文复制引用
Shuhong Tang,Jilai Bian,Mingwu Li..The effects on surgery and preoperative patients with non-small cell lung cancer by preoperative bronchial artery infusion chemotherapy[J].中德临床肿瘤学杂志(英文版),2008,7(8):447-450,4.基金项目
Supported by a grant from the Foundation of Science and Technology of Dalian (No.20039907). (No.20039907)