中国临床康复2002，Vol.6Issue(3)：451-452,2.
中国汉人 X染色体上情感障碍易感性基因的遗传学研究及关联分析
Susceptible gene for affection disorder of chromosome X in Han people of Chinese:genetical study and relative analysis
吴怀安 1闫小华 1邓小敏 1沈其杰1
作者信息
- 1. Shenzhen Institute of Mental Health,Shenzhen 518020,China
- 折叠
摘要
Abstract
Objective In order to detect the Susceptible gene on X chromosome for Han nationality of Chinese who suffer from affective disorder(AD),to explore the association between DXS1114 polymorphism and AD and the feature of genetics.Method We used the technique of the amplified fragment length polymorphism(Amp FLP)to detect the polymorphism distribution of DXS1114 for 40 patients with AD and 40 normal controls.Results We found that there were 4 polymorphism fragments of DXS1114 on the γ -chromosome in AD and normal controls.The result of statistics showed that four polymorphism fragments(117bp.113bp.111bp 109bp)had not significant difference(P>0.05)between patients and normal controls.Conclusion We report that the DXS1114 is not associated with Chinese who suffer from AD.The results indicate that there maybe no a susceptible gene of AD on xq26.1 in our research simples.关键词
DXS1114/micro satellite DNA/polymorphism/affective disorder/associationIntroductionKey words
DXS1114/micro satellite DNA/polymorphism/affective disorder/associationIntroduction分类
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吴怀安,闫小华,邓小敏,沈其杰..中国汉人 X染色体上情感障碍易感性基因的遗传学研究及关联分析[J].中国临床康复,2002,6(3):451-452,2.
