西安医科大学学报2000，Vol.21Issue(5)：452-454,3.
乳腺癌p21WAF1／CIP1表达与激素受体的相关性研究
A study on the correlation between p21WAF1/CIP1 protein expression and hormone
receptors in breast cancer
孙润芹 1陈晓黎 1王康敏 1苏宝山 1黄莺1
作者信息
- 1. 西安交通大学第二医院病理科，西安 710004
- 折叠
摘要
Abstract
Objective To investigate the relationship between p21WAF1/CIP1 protein and ER, PR and histologic grade as well as lymph node metastasis in human breast cancer. Methods By us ing immunohistochemical method, the expression of p21WAF1/CIP1, ER and PR was investigated in 60 breast carcinoma samples. Results It was noted that a significant correlation existed between p21WAF1/CIP1 and ER、PR、p21WAF1/CIP1 expression was related to histologic grade and lymph node metastasis. Conclusion ①Detection of p21WAF1/CIP1 protein may have important reference value for patients with breast cancer to receive endocrine therapy; ②)p21WAF1/CIP1 protein expression is of value in evaluating the degree of differentiation and lymph node metastasis of breast cancer关键词
乳腺癌/p21蛋白/雌孕激素受体/免疫组化Key words
breast cancer/p21WAF1/CIP1 protein/ER/PR/immunohistochemistry分类
医药卫生引用本文复制引用
孙润芹,陈晓黎,王康敏,苏宝山,黄莺..乳腺癌p21WAF1／CIP1表达与激素受体的相关性研究[J].西安医科大学学报,2000,21(5):452-454,3.
