中国组织工程研究与临床康复2008，Vol.12Issue(23)：4546-4548,3.
羟丙基壳聚糖纳米微粒的制备
Preparation of hydroxypropyl-chitosan nano-spheres
摘要
Abstract
Hydroxypropyl-chitosan with substitution degree of 0.56 is prepared by the reaction of chitosan and epoxypropane by controlling condition. The water solubility of modified hydroxypropyl-chitosan is enhanced. When suitable concentration of hydroxypropyl-chitosan water solution responds to certain concentration of sodium polyphosphate based on ion gel method, the hydroxypropyl-chitosan nano-spheres with particle size of 500-700nm are obtained. Transmission electron micrograph shows that the shape of prepared hydroxypropyl-chitosan nano-sphere is uniform.关键词
壳聚糖/羟丙基/纳米微粒/生物材料分类
医药卫生引用本文复制引用
谢宇,尚晓娴,蒋丰兴,胡金刚..羟丙基壳聚糖纳米微粒的制备[J].中国组织工程研究与临床康复,2008,12(23):4546-4548,3.基金项目
江西省自然科学基金资助,课题名称:生物法制备低聚壳聚糖的研究(0620071) （0620071）
航空高校科研基金资助,课题名称:壳聚糖基纳米粒子的制备与表征(EA200502138) the Natural Science Foundation of Jiangxi Province, No. 0620071 （EA200502138）
the Scientific Research Foundation Program of Hangkong High Institions,No.EA200502138 （）
