中国人兽共患病杂志2000，Vol.16Issue(6)：45-47,3.
鼠伤寒沙门氏菌porin诱导BALB／c
小鼠细胞免疫的研究
STUDY ON CELL MEDIAED-IMMUNITY INDUCED BY PORIN OF SALMONELLA TYPHIMURIUM
赵跃武 1赵凤兰 2胡军 2徐友梅2
作者信息
- 1. 河南省人民医院生物治疗研究中心郑州，450003
- 2. 河南医科大学微生物学和免疫学教研室
- 折叠
摘要
Abstract
Aim To investigate cell mediated-immunity induced by porin of Salmonella typhimurium(STM). Methods Level of delayed-type hypersensitivity(DTH), IL-2 of immunized BALB/c mice were determined by footpad swelling,MTT and transfered protective rate of T cells purified by neloy wool were studied with 500LD50 of the bacteria(intraperitoneally). Results A marked level of DTH(3. 6±0. 2,P＜0. 01),IL-2(26.2±4.9,P＜0. 01) and the immuinized T cells transfer protec tive level (42.9％ ,P＜0. 01) was induced by porin from STM. Conclusion These results indicated that porin of STM might in duced stronger CMI in BALB/c mice.关键词
鼠伤塞沙门氏菌porin/迟发性变态反应IL-2/T淋巴细胞转移Key words
Salmonella typhimurium/Porin/Delayed-type hypersensitivity IL- 2/T cell transfer immuity分类
医药卫生引用本文复制引用
赵跃武,赵凤兰,胡军,徐友梅..鼠伤寒沙门氏菌porin诱导BALB／c
小鼠细胞免疫的研究[J].中国人兽共患病杂志,2000,16(6):45-47,3.
