国际医药卫生导报2009，Vol.15Issue(12)：4-6,3.DOI:10.3760/cma.j.issn.1007-1245.2009.12.002
大剂量血管加压素在心肺复苏中的应用观察
Study the effects of high dose vasopressin on cardiopulmonary resuscitation
摘要
Abstract
Objoctive To study the effect of high dose vasopressin on cardiopulmonary resuscitation. Methods 47 patients with cardiac arrest were randomly divided into standard dose epinephrine group (group A, n=17), vasopressin 40 U and standard dose epinephrine group (group B, n=14) and vasopressin 80 U and standard dose epinephrine group (group C, n=16).The rate of spontaneous circulation restoration, the survival rate and the average time of spontaneous circulation restoration were monitored in each group. Results The rates of spontaneous circulation restoration of group A, group B and group C were respoctively 17.6%, 50.0% and 56.3 %. Among them, the rates of spontaneous circulation restoration of group B and group C were significantly higher than that of group A. The survival rate of group C (31.3%) was significantly higher than that of the other two groups (5.9% of group A, 14.3 % of group B). The average time of spontaneous circulation restoration of group B, C was significantly shorter than that of group A. Conclusions Compared with the single administration of standard dose epinephrine or vasopressin 40U and standard dose epinephrine, the administration of high dose vasopressin 80U combined with standard dose epinephrine could significantly shorten the average time of spontaneous circulation restoration, increase the rate of spontaneously circulation restoration and the survival rate during cardiopulmonary resuscitation.关键词
心肺复苏/血管加压素/肾上腺素Key words
Cardiopulmonary resuscitation/Vasopressin/Epinephrine分类
医药卫生引用本文复制引用
卓名,周宁,李志文,姚为学,苏耿,陈粤明,李春华..大剂量血管加压素在心肺复苏中的应用观察[J].国际医药卫生导报,2009,15(12):4-6,3.基金项目
湛江市科技攻关项目(2008C04003) （2008C04003）
