山东中医药大学学报2000，Vol.24Issue(6)：461-463,3.
丙肝康对大鼠肝损伤及免疫功能的影响
IMMUNOLOGIC EFFECTS OF BINGGANKANG ORAL LIQUID ON RATS WITH INJURED LIVER
摘要
Abstract
Objective:To investegate the immunity effects of Binggankang (BGK) oral liquid on experimentalliver fibrosis and function of immune response in rats. Methods :The livers of rats were injured by bovine serum al-bumen from vein. After three times ,BGK was orally administrated to some injured rats. These indexes needed to beobserved: body weight, TP, AL3, phagocytic index to staphylococcus, Fc, C3b receptor numbers in macrophage,ALT ,AST ,circulatory immune complex (CIC) ,MAO ,hydroxproline in liver ,liver morphoachitecture ,splenic mor-phcachitecture,percent of T lymphocytes in rats serum. Results:The levels of phagocytic index to staphylococcus,Fc ,C3b receptor numbers ,ALB,percent of T lymphocytes in BGK group were higher than those in the model group(P＜0.05 ,P＜0.01). These levels of ALT, MAO,CIC, hydroxproline in liver were lower than those in the modelgroup (P＜0.05 ,P＜0.01). Conclusion :BGK could obviously reduce the degree of hepatofibrosis in rats and con-gestion and hydrops in spleen,increase immune function in injured rats,eliminated CIC and protect effectively theinjured liver of rats.关键词
丙肝康/肝损伤/免疫功能/实验研究Key words
BGK oral liquid/liver injury/immunity/rats分类
医药卫生引用本文复制引用
彭勃,任周新,黄朝阳,赵文霞..丙肝康对大鼠肝损伤及免疫功能的影响[J].山东中医药大学学报,2000,24(6):461-463,3.基金项目
河南省科技攻关资助项目 编号9811706437 （）
