中国神经再生研究（英文版）2008，Vol.3Issue(4)：461-464,4.
Wernicke encephalopathy Clinical presentation and MR images in two nonalcoholic patients
Wernicke encephalopathy Clinical presentation and MR images in two nonalcoholic patients
He Zhang 1Jun Wu 1Zhiping Hu 1Bo Xiao 2Guoliang Li2
作者信息
- 1. Department of Neurology, Xiangya Second Hospital, Central South University,Changsha 410011, Hunan Province, China
- 2. Department of Neurology, Xiangya Hospital, Central South University, Changsha 410011, Hunan Province, China
- 折叠
摘要
Abstract
The aim of the present study was to investigate the importance of and correlation between clinical presentations and magnetic resonance imaging (MRI) of two different cases of nonalcoholic Wernicke encephalopathy. Case 1: A 63-year-old man with a diagnosis of incomplete mechanical intestinal obstruction. His abdominal symptoms were improved by gastrointestinal decompression, but blurred vision, hypoacusis, dizziness, and unsteady gait were noted. His illness deteriorated to confusion on day seven. MRI showed hyperintense lesions in the medial thalami, tectum of the midbrain, and the periaqueduct region on T2- and diffusion-weighted images. Thiamine therapy was commenced immediately with good results. Case 2: A 22-year-old woman was admitted for sudden-onset confabulation and unsteady gait after hyperemesis gravidarum. She had no history of alcohol or any medication. Brain MRI was normal. The patient experienced relief after Vitamin B1 treatment. These results suggest that brain MRI can define characteristic abnormalities in Wernicke encephalopathy, and that diffusion-weighted imaging may improve the diagnosis sensitivity. In addition, the MRI images may be correlated to the clinical stage and severity of the disease. Nevertheless, the clinical features are essential for correct diagnosis.关键词
wernicke encephalopathy/ magnetic resonance imaging/ clinical presentationKey words
wernicke encephalopathy/ magnetic resonance imaging/ clinical presentation分类
医药卫生引用本文复制引用
He Zhang,Jun Wu,Zhiping Hu,Bo Xiao,Guoliang Li..Wernicke encephalopathy Clinical presentation and MR images in two nonalcoholic patients[J].中国神经再生研究（英文版）,2008,3(4):461-464,4.
