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Differential effects of controlled hypotension on gastric intramucosal pH and post-operational gastrointestinal functional under two different anesthesia methods

Guanglei Wang Junli Cao Gongjian Liu

南京医科大学学报(英文版)2008,Vol.22Issue(1):47-51,5.
南京医科大学学报(英文版)2008,Vol.22Issue(1):47-51,5.

Differential effects of controlled hypotension on gastric intramucosal pH and post-operational gastrointestinal functional under two different anesthesia methods

Differential effects of controlled hypotension on gastric intramucosal pH and post-operational gastrointestinal functional under two different anesthesia methods

Guanglei Wang 1Junli Cao 1Gongjian Liu1

作者信息

  • 1. Department of Anesthesiology, the Affiliated Hospital of Xuzhou Medical College, Xuzhou, 221002, Jiangsu Province, China
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摘要

Abstract

Objective: To observe the effects of controlled hypotension on gastric intramucosal pH and post-operational gastrointestinal functions using two specific anesthesia methods. Methods: Thirty patients(ASA Ⅱ)scheduled for ectomy of hepatocarcinoma, were randomly assigned to two groups: epidural block combined with intravenous anesthesia group(E group) and inhalation anesthesia group(G group). Gastric PgCO2 and pHi were monitored at different time points, before theintravenous induction of controlled hypotension, after 1 h and 2 h, and 1 h after the termination of controlled hypotension. In the meanwhile, the artery blood gas was analyzed. Results: There was no significant difference in blood gas indexes between E group and G group. However, pHi decreased significantly after 1 h and 2 h of controlled hypotension(P<0.05), and during the same periods PgCO2 increased significantly(P<0.05 or P<0.01), the time of bowel movement and defecating deferred significantly shorter in G group patients, when compared with E group patients. Conclusion: Epidural block in combination with general anesthesia can improve gastrointestinal blood flow during controlled hypotension and facilitates post-operational recovery of gastrointestinal functions.

关键词

anesthesia/ epidural/ general anesthesia/ controlled hypotension/ gastric mucosa

Key words

anesthesia/ epidural/ general anesthesia/ controlled hypotension/ gastric mucosa

分类

医药卫生

引用本文复制引用

Guanglei Wang,Junli Cao,Gongjian Liu..Differential effects of controlled hypotension on gastric intramucosal pH and post-operational gastrointestinal functional under two different anesthesia methods[J].南京医科大学学报(英文版),2008,22(1):47-51,5.

南京医科大学学报(英文版)

1674-8301

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