中德临床肿瘤学杂志(英文版)2008,Vol.7Issue(8):484-486,3.
Clinical study on radiotherapy combined with surgical treatment of 162 patients with cervical cancer
Clinical study on radiotherapy combined with surgical treatment of 162 patients with cervical cancer
Xiaopeng Zhong 1Xukun Tong 1Lingfang Yang 1Donglin Yuan 1Huigao Cai1
作者信息
- 1. Tumor Radiotherapy Centre, Huizhou Central People's Hospital of Guangdong Province, Huizhou 516001, China
- 折叠
摘要
Abstract
Objective: To compare the 5-year survival rates and complications of internal and external irradiation therapy combined with operation in patients with Ⅱ-Ⅲ period of cervical cancer.Methods: 162 cervical cancer patients after the whole palace resection pelvic lymphadenectomy were divided into three groups, and then accepted radiotherapy.The first group with 91 cases was accepted internal and external irradiation therapy before operation; the second group with 37 cases was given internal irradiation therapy before operation; the third group with 34 cases was given routine postoperative radiotherapy.External irradiation used 60Co irradiation or a linear accelerator, to the whole basin, and the irradiation dose of "B" point in preoperative radiotherapy was 26-30 Gy, in postoperative radiotherapy was 46-50 Gy; intraluminal brachytherapy used 192lr,the dose of "A" point was 5-15 Gy.Results: The 5-year survival rate of preoperative combined radiotherapy group was 78.0%(71/91), preoperative intracavitary radiotherapy group 64.9% (24/37), and postoperative radiotherapy group 35.3% (12/34).Comparing the 5-year survival rates of the preoperative combined and postoperative irradiation groups, there was significant difference (P<0.05).The major complications were radioactive proctitis and cystitis, the complication incidences of three groups were 35.2% (32/91), 32.4% (12/37), 38.2% (13/34), respectively, and the differences were not statistically significant (P>0.05).Conclusion: The intraluminal brachytherapy plus external irradiation can significantly increase the 5-year survival rate of patients with Ⅱa-Ⅲa stages, and the incidence of complications was not significant difference.关键词
cervical cancer/radiotherapy/combination therapy/prognosisKey words
cervical cancer/radiotherapy/combination therapy/prognosis分类
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Xiaopeng Zhong,Xukun Tong,Lingfang Yang,Donglin Yuan,Huigao Cai..Clinical study on radiotherapy combined with surgical treatment of 162 patients with cervical cancer[J].中德临床肿瘤学杂志(英文版),2008,7(8):484-486,3.