广东医学2001，Vol.22Issue(6)：487-488,2.
慢性肺心病患者血浆α-颗粒膜蛋白及血管性假血友病因子的临床研究
A clinical study on plasma alpha granule membrane protein-140 and von willebrand factor levels in patients with chronic pulmonary heart disease
摘要
Abstract
Objective To study the activation of platelets in vivo and endothelial in patients with chronic pulmonary heart disease. Methods Plasma alpha granule membrane protein-140(GMP-140) and von willebrand factor (vWF) levels were determined by enzyme-linked immunosorbent assay in cor pulmonale exacerbation, cor pulmonale remission stage and in normal control. Results The levels of GMP-140 and vWF in cor pulmonale exacerbation and remission stage were significantly higher than that of normal control group. And the levels of plamsa GMP-140 and vWF in corpulmonals exacerbation were higher than that in remission stage.Conclusion Enhanced active action of platelets and injury in vascular endothlial juries may participate in the formation and progression of pulmonary heart disease.关键词
肺心病/α-颗粒膜蛋白/血管性假血友病因子分类
医药卫生引用本文复制引用
张虹,孙玉汾,黄兰卿,卢岑,王小潮..慢性肺心病患者血浆α-颗粒膜蛋白及血管性假血友病因子的临床研究[J].广东医学,2001,22(6):487-488,2.基金项目
本课题为江门市2000年科技攻关计划项目(编号：00G003-01) （编号：00G003-01）
