中国现代医学杂志2005，Vol.15Issue(4)：490-492,496,4.
IgA肾病肾小动脉增厚的意义
Significance of arteriolar hypertrophy in IgA nephropathy
摘要
Abstract
[Objective] To explore the significance of arteriolar hypertrophy in IgA nephropathy. [Methods] A case control study was carried out in 93 cases with IgA nephropathy (2002.3～2003.8) diagnosed by renal biopsy in our department. Univariate analysis and multivariate logistic regression analysis were performed to analyze the clinical and pathologic materials of 93 IgAN patients. [Results] Of the 93 IgAN patients, 59.1% were with arteriolar hypertrophy. Among these patients, 63.6% were mild arteriolar hypertrophy; 27.3% were moderate arteriolar hypertrophy; 9.1% were severe arteoliar hypertrophy. The patients with arteoliar hypertrophy had a relatively severe condition than those without arteriolar hypertrophy (P ＜0.01). The patients with severe arteoliar hypertrophy had more severe condition than those with mild or moderate arteoliar hypertrophy (P ＜0.01). The higher the pathological grade of the nephropathy, the more severe the arteoliar lesions (P ＜0.01). Multivariate logistic regression analysis showed that the significant influencing factors on arteoliar hypertrophy included hypertension, high serum creatinine, global glomerular sclerosis (≥50%), interstitial inflammation (≥50%). [Conclusions] In patients with IgAN, arteriolar hypertrophy can reflect the disease degree and can be used as an important histological prognostic indicator.关键词
IgA肾病/小动脉/病理Key words
IgA nephropathy/arteriole/pathology分类
医药卫生引用本文复制引用
李寒,刘章锁..IgA肾病肾小动脉增厚的意义[J].中国现代医学杂志,2005,15(4):490-492,496,4.基金项目
Zhengzhou University Doctor's fund （）
