昆明医学院学报2001，Vol.22Issue(1)：49-52,4.
左旋荷包牡丹碱抗实验性心律失常的研究
Anti-Arrythmic Effects of L-Dicentrine
李惠兰 1李牧 1刘星玲 1苏善国 2韩毅2
作者信息
- 1. 昆明医学院药理教研室
- 2. 昆明医学院生理教研室,
- 折叠
摘要
Abstract
To observe Antiarrhythmic effects of L-dicentrine．Methods using experimented model of arrhythmials．Results: L-dicentrine iv l0 mg/kg could convert BacRinduccd arrhythmia into sinus rhythm in rats,and could significantly increase the tolerant dose of aconine to produce Ventricular fibrillation (VF) and Cardiac ［rrest (ca) in rats． The drug could also decrease the incidence of VF and CP by cardiac rats and by chloroform in mice． L-dicelltrine had protective effects on ouabain ind uced Arrhythmias in guined pigs and on adrenalice induced arrhythmias in rabbit s ． The drug might also inhibit the arrhymias induced by stimulation ofhypothaplu s． Conclusion: L-dicenirine have significant antiarrhythmic properties．关键词
左旋荷包牡丹/心律失常/保护作用分类
医药卫生引用本文复制引用
李惠兰,李牧,刘星玲,苏善国,韩毅..左旋荷包牡丹碱抗实验性心律失常的研究[J].昆明医学院学报,2001,22(1):49-52,4.
