眼科学报2002，Vol.18Issue(1)：49-53,5.
Experimental Study of Effect of Perfluorohexyloctane to Retina
Experimental Study of Effect of Perfluorohexyloctane to Retina
Chunfang Li 1Xiaoyan Ding 1Lin Lu 1Guanguang Feng 1Huling Zheng1
作者信息
- 1. Zhongshan Ophthalmic center, Sun Yet-san University, Guangzhou 510060 , China
- 折叠
摘要
Abstract
Objective: To investigate the effect of perfluorohexvloctane to the retina of rabbit eyes.Methods: Perfluoroh-exyloctane (experimental group) or BSS(control group) intovitreous cavities of fifteen vitrectomized New Zealand white rabbits. A slit-lampbiomicroscope and an indirect ophthalmoscope were used to examine all the eyes pre- andpostoperation. Histopathological examination was performed after the rabbits weresacrificed. Results:Perfluorohexyloctane was injected into the vitreous cavity forming a single largeclear globe. No retinal detachment and cataract were found. The edema of outer plexiformlayer was significant, and then get thin, inner nuclear layer and ganglion cell bodies hada darker cytop: lasm and nucleoplasm. Conclusions: Perfluorohexyloctane in vitreous cavity had significant side effects on retinaAs a silicone solvent, it should be removed out completely after injection. We don′trecommend to use it as a new intraocular temponade.关键词
retina/perfluorohexyloctane/vitreous substitute/vitrectomvKey words
retina/perfluorohexyloctane/vitreous substitute/vitrectomv分类
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Chunfang Li,Xiaoyan Ding,Lin Lu,Guanguang Feng,Huling Zheng..Experimental Study of Effect of Perfluorohexyloctane to Retina[J].眼科学报,2002,18(1):49-53,5.
