中国当代儿科杂志2003，Vol.5Issue(6)：497-499,3.
窒息新生儿脐血乳酸值的临床意义
Clinical Significance of Cord Blood Lactate in Neonates with Asphyxia
摘要
Abstract
Objective It is clinically insufficient to assess the severity and prognosis of neonatal asphyxia only according to Apgar score and blood gas measurement. In order to find more sensitive and specific indexes, the clinical significance of cord blood lactate in neonates with asphyxia was studied. Methods The lactate level and the pH value of cord arterial bloot were determined in 31 term infants with perinatal asphyxia (further divided into the mild and the severe asphyxia groups) and 30 normal neonates (the control group). At the 14th day after birth, 20-item neonatal behavioral neurological assessment (NBNA) was taken for each subject. Results The levels of cord blood lactate in the mild and severe asphyxia groups [ (6.42 + 0.14) and (10.77 + 0.12) mmol/L] were significantly higher than that in the control group [(4.20 +0.15) rmmol/L] ( P ＜ 0.01). The pH values in the mild and severe asphyxsia groups weremarkedly lower than that of the control group [(7.16+0.07) vs (7.18+0.11); (7.04+0.09) vs (7.18+0.11)]( P＜ 0.01 ). There were significant differences in the lactate level and pH value between the mild and severe asphyxia groups( P ＜0.01). The lactate level was negatively correlated with the pH value and the score of NBNA ( r = -0.76 and-0.85, respectively, both P ＜ 0.01). Conclusions Cord blood lactate may be a useful index in evaluating the severity and short-term prognosis in neonates with perinatal asphyxia.关键词
窒息/乳酸/新生儿行为神经测定/新生儿Key words
Asphyxia/Lactate/Neonatal Behavioral Neurological Assessment/Newborn分类
医药卫生引用本文复制引用
旷寿金,易靖,李颖,周昌菊..窒息新生儿脐血乳酸值的临床意义[J].中国当代儿科杂志,2003,5(6):497-499,3.基金项目
Scientific Research Foundation Supported by Hunan Public Health Department (No. Y02 - 055) （No. Y02 - 055）
