中国人兽共患病杂志2001，Vol.17Issue(1)：50-51,97,3.
动态检测特异性免疫复合物在脑囊虫病治疗过程的意义
DYNAMIC MONITORING OF THE SPECIFIC IMMUNE COMPLEX DURING TREATMENT IN NEUROCYSTICERCOSIS
张明霞 1林尔昕 2王淑民 2崔琢2
作者信息
- 1. 蚌埠医学院微生物学教研室 蚌埠，233003
- 2. 蚌埠医学院附院传染病科
- 折叠
摘要
Abstract
Aim To observe the dynamic changes of specific immune complexover all courses of drug administration of patients with neurocysticercosis. Methods By using a double mono-cloned antibody sandwich ELISA assay the specific immune complex was detected.Employed anti-human IgG, IgM McAb as coated material, and HRP labeled anti-cysticerci McAb as recognizing system, specific immune complexes that extracted in sera were monitored. Results The immune complex level of IgG class rose significantly after the 1st course (P＜0.05), and then gradually dropped off (P＜0.01). On the other hand, that of IgM class did not change significantly after 1st course of treatment. It gradually declined with advancing course of drug administration (P＜0.01). The incidence rate of clinical worsening after 1st course of treatment was the highest one among all courses (P＜0.005).Conclusion This study indicates that immune complex level of IgG class is associated with the clinical worsening and the efficacy of therapy.关键词
脑囊虫病/免疫复合物/ELISA分类
医药卫生引用本文复制引用
张明霞,林尔昕,王淑民,崔琢..动态检测特异性免疫复合物在脑囊虫病治疗过程的意义[J].中国人兽共患病杂志,2001,17(1):50-51,97,3.
