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单纯性卵巢未成熟型畸胎瘤肝脏周围复发的临床特点、诊断和治疗

樊庆泊 黄惠芳 连利娟 郎景和

中华医学杂志(英文版)2001,Vol.114Issue(5):506-509,4.
中华医学杂志(英文版)2001,Vol.114Issue(5):506-509,4.

单纯性卵巢未成熟型畸胎瘤肝脏周围复发的临床特点、诊断和治疗

Characteristics, diagnosis and treatment of hepatic metastasis of pure immature ovarian teratoma

樊庆泊 1黄惠芳 1连利娟 1郎景和1

作者信息

  • 1. 中国医学科学院中国协和医科大学北京协和医院妇产科,
  • 折叠

摘要

Abstract

Objective To analyze the characteristics of hepatic metastasis of pure immature ovarian teratoma and explore its proper diagnosis and treatment.Methods Eighteen cases of hepatic metastasis of pure immature ovarian teratoma were included in this study. The clinical stage, operation, chemotherapy and histopathology of primary and secondary tumors as well as the data from long term follow-ups were analyzed retrospectively,Results All of the hepatic metastatic tumors were located on the surface of the liver. 61.1% (11/18) of them were clinical stage Ⅲ and 44.4% (8/18) were grade 1 at first operation. The hepatic metastatic rate was 16.7% (3/18) in the standard adjuvant chemotherapy group but increased markedly to 31.2% (15/48) in the irregular chemotherapy group. Auxiliary diagnostic methods could not indicate the correct results. The surgical resection rate of hepatic metastasis of pure immature ovarian teratoma was 94.4% (17/18). There were less complications in the group with tumor diameter less than 15 cm. The follow-up time ranged from 3 to 205 months with a mean of 20.9 months. The 3-year-survival rate was 77.8% (14/ 18), and mortality rate was 22.2%. The 5- and 10-year-survival rate was 55.6% (10/18) and 38.9% (7/18), respectively. The rate of loss in follow-up was 22.2% (4/18) and 38.9% (7/18), respectively, and one patient has survived for more than 17 years.Conclusions The hepatic metastatic rate of pure immature ovarian teratoma could be decreased using standard adjuvant chemotherapy. Suitable surgical treatment could reduce complications and improve the prognosis for patients.

关键词

卵巢未成熟型畸胎瘤肝脏周围转移

分类

医药卫生

引用本文复制引用

樊庆泊,黄惠芳,连利娟,郎景和..单纯性卵巢未成熟型畸胎瘤肝脏周围复发的临床特点、诊断和治疗[J].中华医学杂志(英文版),2001,114(5):506-509,4.

中华医学杂志(英文版)

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