中华医学杂志（英文版）2002，Vol.115Issue(4)：509-512,4.
心电图U波与左心室中层心肌关系的实验研究
Relationship between the U wave on electrocardiogram and the midmyocardium of the left ventricular wall
摘要
Abstract
Objective To investigate the relationship between the U wave on electrocardiogram and the midmyocardium in rabbit left ventricle free wall in vivo. Methods The monophasic action potentials in the epicardium, midmyocardium, and endocardium of the left ventricle free wall were recorded simultaneously in 16 rabbits. The rabbits were then given an intravenous injection of Sotalol (1, 1.5 and 2.0mg/kg) in 30 minutes intervals, and measurements were taken.Results In the basic condition, there were no U wave on electrocardiogram. The U wave appeared after the intravenous Sotalol at 1.5mg/kg, and the U wave became greater with increased dosage of intravenous Sotalol (2mg/kg). The repolarization duration of the midmyocardium was prolonged longer than that of the epicardium and endocardium by Sotalol, and the repolarization duration of the epicardium coincided with the apex of the T wave, The repolarization duration of the midmyocardium coincided with the end point of the U wave.Conclusion The U wave may originate from the delayed repolarization of the midmyocardium.关键词
U波 中层心肌 单相动作电位 SotalolKey words
U wave/midmyocardium/monophasic action potential/Sotalol分类
医药卫生引用本文复制引用
张存泰,李运田,陆再英,吴杰,王晨..心电图U波与左心室中层心肌关系的实验研究[J].中华医学杂志（英文版）,2002,115(4):509-512,4.基金项目
This study was supported by the Health Ministry Science Fund of China (No. 98-2-095). （No. 98-2-095）
