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保留喉功能疗法在喉癌 T3期病例中的应用探讨

夏良平 曾宗渊 陈福进 郭朱明 许光普 张诠

癌症2001,Vol.20Issue(5):511-514,4.
癌症2001,Vol.20Issue(5):511-514,4.

保留喉功能疗法在喉癌 T3期病例中的应用探讨

Modalities of Preserving Laryngeal Functions in Patients with T3 Laryngeal Carcinoma

夏良平 1曾宗渊 1陈福进 1郭朱明 1许光普 1张诠1

作者信息

  • 1. 中山医科大学肿瘤防治中心头颈科,
  • 折叠

摘要

Abstract

Objective: The aim of this study was to investigate the best choice of the three treatment modalities of preserving laryngeal functions in T3 laryngeal carcinoma. Methods: There were 94 cases with T3 laryngeal carcinoma (Stage Ⅲ and Ⅳ ) who were treated by three kinds of modalities of preserving laryngeal functions: definitive radiotherapy, salvage surgery for the failures of definitive radiotherapy, partial laryngectomy. We compared their survival curve, recurrence rate of the primary and secondary site, and the complications. Results: The survival curve of the partial laryngectomy groups was better than that of the definitive radiotherapy group in supraglottic carcinoma (P=0.0248). In glottial carcinoma, the survival curve of partial laryngectomy group and salvage surgery group were insignificantly different, both of them were better than that of definitive radiotherapy group (P=0.0075). The complication rate of the salvage surgery group was significantly higher than that of partial laryngectomy group (60% Vs 16.7% ); We regarded the definitive radiotherapy group and salvage surgery group as one group, it's primary site recurrence rate was significant higher than that of partial laryngectomy group (45.8% Vs 19.4% ). Conclusion: Partial laryngectomy is the most effective way among the three modalities of preserving laryngeal functions to treat T3 laryngeal carcinoma.

关键词

喉肿瘤/外科手术/保留喉功能/治疗方式/生存率分析/复发率

分类

医药卫生

引用本文复制引用

夏良平,曾宗渊,陈福进,郭朱明,许光普,张诠..保留喉功能疗法在喉癌 T3期病例中的应用探讨[J].癌症,2001,20(5):511-514,4.

癌症

OA北大核心CSCD

1000-467X

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