中华医学杂志（英文版）2003，Vol.116Issue(4)：514-516,3.
β-carotene protects rats against bronchitis induced by cigarette smoking
β-carotene protects rats against bronchitis induced by cigarette smoking
庞宝森 1王辰 1翁心植 1唐小奈 1张红玉 1牛淑洁 1毛燕玲 1辛平 1黄秀霞 1张海燕 1祝锦1
作者信息
- 1. Beijing Institute of Respiratory Medicine, Beijing Chaoyang Hospita, Capital University of Medical Sciences, Beijing 100020, China
- 折叠
摘要
Abstract
Objective To investigate the protective effects of β-carotene in rats against the development of chronic bronchitis induced by cigarette smoking. Results Long-term cigarette smoking caused an obvious increase in the amount of IL-6, IL-8 and LPO and a sharp decrease in the levels of NO and SOD in smoking animals compared to controls. β-carotene intake reversed all the changes induced by smoking and alleviated the pathological changes caused by chronic bronchitis. Conclusions Quantitative oral intake of β-carotene had protective effects against chronic bronchitis induced by long-term cigarette smoking, which was associated with the increased production of NO, the clearance of some oxidative free radicals (OFR) and the alleviation of chronic inflammation.关键词
smoke/bronchitis/β-caroteneKey words
smoke/bronchitis/β-carotene分类
医药卫生引用本文复制引用
庞宝森,王辰,翁心植,唐小奈,张红玉,牛淑洁,毛燕玲,辛平,黄秀霞,张海燕,祝锦..β-carotene protects rats against bronchitis induced by cigarette smoking[J].中华医学杂志（英文版）,2003,116(4):514-516,3.
