国际医药卫生导报2009，Vol.15Issue(4)：52-55,4.DOI:10.3760/cma.j.issn.1007-1245.2009.04.022
氟比洛芬酯预防鼻内窥镜手术七氟醚全麻术后躁动的临床研究
Intravenous flurbiprofen axetil injection as a suppressant of agitation after functional endosoopic sinus surgery with sevoflurane general anesthesia
许冬妮 1林道炜 1李艳萍 1黄海量1
作者信息
- 1. 510120,广州,中山大学孙逸仙纪念医院麻醉科
- 折叠
摘要
Abstract
Objective To investigate the effects of the intravenously administra-tion of flurbiprofen axetil injection on agitation after functional endoscopic sinus surgery with sevoflurane general anesthesia. Methods A total of 40 patients aged from 18 years to 60 years in good health (ASA physical status Ⅰ～Ⅱ ) undergoing elective functional endoscopic sinus surgery were randomly and respectively divided into three groups. The patients were induced with fentanyl and propofol and rocuronium, and maintained with 2.5%～3.5% sevoflurane and oxygen. In group T, flurbiprofen axetil injection 50mg were administrated 15 minutes before the end of operation, and fentanyl 1μg/kg in group F, and in group C was given an equal volume of NS. The heart rate (HR), mean arterial blood pressure (MAP) were assessed during the anesthesia. The extubation time, waking time, postoperative agitation, nausea and vomiting were observed and recorded. Results The agitation was remarkably suppressed in group T and group F than group C. And there was a significant difference in mean heart rate and mean arterial blood pressure in group C compared with group T and F. And the extubation time and waking time were almostly the same in group T and group C, and both shorter than that in group F. The rate of nausea and vomiting were not increased in the group T. Conelusion It is safe and feasible to give flurbiprofen axetil injection 50mg to reduce agitation after functional endoscopic sinus surgery with sevoflurane general anesthesia.关键词
氟比洛芬酯/七氟醚/躁动:FESS术Key words
Flurbiprofen Axetil Injection/Sevoflurane/Agitation/FESS分类
医药卫生引用本文复制引用
许冬妮,林道炜,李艳萍,黄海量..氟比洛芬酯预防鼻内窥镜手术七氟醚全麻术后躁动的临床研究[J].国际医药卫生导报,2009,15(4):52-55,4.
