眼科学报2000,Vol.16Issue(1):53-55,3.
The Analysis of Pedigree GZ (Guangzhou) . 1with Primary Open Angle Glaucoma
The Analysis of Pedigree GZ (Guangzhou) . 1with Primary Open Angle Glaucoma
摘要
Abstract
Purpose: To analyze the hereditary modality of primary open-angle glaucoma in China.Methods: The genetic form of Pedigree GZ. 1 was analyzed using Mandalian hereditary rules.Results: Pedigree GZ. 1 had following characteristics: 1) The pedigree had four generations, and there existed POAG patients in each generation; 2) Each patient had a parent with POAG. If the parents didn't suffer from the disease, their children would not. 3) The incidence of POAG in the relatives of the patients was 1/2. In addition,The age of onset, intraocular pressure, fundus and prognosis was different from each other in the patients.Conclusions: 1 ) Pedigree GZ. 1 is inherited as an autosomal dominant trait. 2) There exists individual differences of clinical manifestations in POAG patients. Eye Science 2000; 16: 53~ 55.关键词
primary open-angle glaucoma, pedigree GZ. 1Key words
primary open-angle glaucoma, pedigree GZ. 1引用本文复制引用
Yehong Zhuo,Jian Ge,Mci Wang,Haiquan Liu,Minkai Lin..The Analysis of Pedigree GZ (Guangzhou) . 1with Primary Open Angle Glaucoma[J].眼科学报,2000,16(1):53-55,3.基金项目
Supported by grants from Nature Science Fundation of China(No. 39770789, 39800163) and Guangdong province(No. 980112). (No. 39770789, 39800163)