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首页|期刊导航|眼科学报|The Analysis of Pedigree GZ (Guangzhou) . 1with Primary Open Angle Glaucoma

The Analysis of Pedigree GZ (Guangzhou) . 1with Primary Open Angle Glaucoma

Yehong Zhuo Jian Ge Mci Wang Haiquan Liu Minkai Lin

眼科学报2000,Vol.16Issue(1):53-55,3.
眼科学报2000,Vol.16Issue(1):53-55,3.

The Analysis of Pedigree GZ (Guangzhou) . 1with Primary Open Angle Glaucoma

The Analysis of Pedigree GZ (Guangzhou) . 1with Primary Open Angle Glaucoma

Yehong Zhuo 1Jian Ge 1Mci Wang 2Haiquan Liu 1Minkai Lin1

作者信息

  • 1. Zhongshan Ophthalmic Center, Sun Yet-sen University of Medical Sciences, Guangzhou 510060, China
  • 2. Sun Yet-sen Hospital, Sun Yet-sen University of Medical Sciences, Guangzhou 510060, China
  • 折叠

摘要

Abstract

Purpose: To analyze the hereditary modality of primary open-angle glaucoma in China.Methods: The genetic form of Pedigree GZ. 1 was analyzed using Mandalian hereditary rules.Results: Pedigree GZ. 1 had following characteristics: 1) The pedigree had four generations, and there existed POAG patients in each generation; 2) Each patient had a parent with POAG. If the parents didn't suffer from the disease, their children would not. 3) The incidence of POAG in the relatives of the patients was 1/2. In addition,The age of onset, intraocular pressure, fundus and prognosis was different from each other in the patients.Conclusions: 1 ) Pedigree GZ. 1 is inherited as an autosomal dominant trait. 2) There exists individual differences of clinical manifestations in POAG patients. Eye Science 2000; 16: 53~ 55.

关键词

primary open-angle glaucoma, pedigree GZ. 1

Key words

primary open-angle glaucoma, pedigree GZ. 1

引用本文复制引用

Yehong Zhuo,Jian Ge,Mci Wang,Haiquan Liu,Minkai Lin..The Analysis of Pedigree GZ (Guangzhou) . 1with Primary Open Angle Glaucoma[J].眼科学报,2000,16(1):53-55,3.

基金项目

Supported by grants from Nature Science Fundation of China(No. 39770789, 39800163) and Guangdong province(No. 980112). (No. 39770789, 39800163)

眼科学报

OACSTPCDMEDLINE

1000-4432

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