中国组织工程研究与临床康复2009，Vol.13Issue(27)：5389-5392,4.DOI:10.3969/j.issn.1673-8225.2009.27.040
脂肪间充质干细胞移植治疗阿尔茨海默病
Adipose derived mesenchymal stem cell transplantation for Alzheimer's disease
摘要
Abstract
Alzheimer's disease is an irreversible neurodegenerative disease characterized by progressive neuronal loss. To date, there has been no effective medicine or therapy for neurodegenerative disease. With development of stem cell technique and theory, neural stem cell transplantation has been found to be prospective in Alzheimer's disease treatment. However, it was challenged by the deficiency of autologous neural stem cell, which can bypass immunological barrier. Compared with neural stem cells, mesenchymal stem cells exhibit extensive resources, such as liver, bone marrow and adipose, and multiple differentiations into bone, muscle or adipose. Considering the easy access, the minor trauma to the patients, and the neuron differentiation potential of adipose derived mesenchymal stem cells (A-MSC), we hypothesize that A-MSC graft is a potential and innovative strategy for the treatment of Alzheimer's disease.关键词
脂肪间充质干细胞/移植/阿尔茨海默病分类
医药卫生引用本文复制引用
牛颖,龚锴,敖强,赵南明,张秀芳,公衍道..脂肪间充质干细胞移植治疗阿尔茨海默病[J].中国组织工程研究与临床康复,2009,13(27):5389-5392,4.基金项目
清华裕元医学科学研究基金(20240000514) （20240000514）
北京科委基金(H060920050430) （H060920050430）
生物膜与膜生物国家重点实验室基金Tsinghua-Yue-Yuen Medical Sciences Fund, No. 20240000514 （）
the Beijing Science and Technology Commission Foundation, No. H060920050430 （）
a grant from the Stat Key Laboratory of Biomembrane and Membrane Biotechnology （）
