中国组织工程研究与临床康复2009，Vol.13Issue(27)：5397-5400,4.DOI:10.3969/j.issn.1673-8225.2009.27.042
人脂肪源间充质干细胞治疗ABO血型不合造血干细胞移植后的顽固性单纯红细胞再生障碍性贫血2例
Human adipose tissue-derived mesenchymal stem cells for treatment of refractory pure red cell aplasia after major ABO-incompatible hematopoietic stem cell transplantation
摘要
Abstract
The present study retrospectively analyzed 2 patients suffering from refractory pure red cell aplasia after major ABO-incompatible hematopoietic stem cell transplantation who received treatment in the Henan Institute of Haematology between April 2004 and February 2006. Patient 1 was a 25-year-old female with acute lymphocytic leukemia in second remission, and patient 2 was a 16-year-old gid with acute myeloid leukaemia in second remission. The two patients received a transplant of human adipose tissue-dedved mesenchymal stem cells (1.0×106/kg). Both of them acquired rapid recovery from pure red cell aplasia without any side effects. These findings suggest that adipose tissue-dedved mesenchymal stem cells seem to be a promising therapeutic option in patients with refractory pure red cell aplasia after ABO-incompatible hematopoietic stem cell transplantation, in whom conventional treatment fails.关键词
造血干细胞移植/单纯红细胞再生障碍性贫血/间充质干细胞分类
医药卫生引用本文复制引用
李玉富,李宁,宋永平,张龚莉,林全德,魏旭东,房佰俊..人脂肪源间充质干细胞治疗ABO血型不合造血干细胞移植后的顽固性单纯红细胞再生障碍性贫血2例[J].中国组织工程研究与临床康复,2009,13(27):5397-5400,4.基金项目
河南省杰出青年基金(0612000900)Excellent Youth Foundation of Henan Scientific Committee, No. 0612000900 （0612000900）
