临床医学工程2009，Vol.16Issue(7)：54-55,2.
糖皮质激素联合长效β2受体激动剂治疗轻中度哮喘的临床疗效
The Clinical Effect of Glucocorticoid Combined with Long-Acting β2-Adrenergic Acceptor Agonist Treating Mild to Moderate Asthma
卢建新1
作者信息
- 1. 汕尾市人民医院,广东,汕尾,516600
- 折叠
摘要
Abstract
Objective To observe the clinical effect of glueocorticoid combined with Iong-actingβ2-adrenergic aeceptor agonist treating mild to moder-ate asthma. Methods 80 patients with mild to moderate asthmatic were chosen out and divided into ta-eatment group and control group with each group 40 cases. Patients in treatment group were treated with salmaterol combined with bodesonide, while patients in control group were treated only with budesonide. Results The efficiency rate was 87.5% in treatment group, 75.0% in control group. Although the efficiency rate of treatment group increased more than that of control group, there wasn't significant difference(P >0.05). The FEV1 and PEF of the two groups improved more significantly than those of pre-treatment (P <0.05), but after treatment, the FEV1 and PEF of treatment group had more significant improvement than those of control group (P <0.05). As to the adverse reactions, con-trol group had 2 cases of hoarseness, 3 cases of palpitation and 1 case of abdominal discomfort, while treatment group only had 2 cases of hoarseness. Conclu-sion Therapy of combined long-actingβ2-adrenergic acceptor agonist can reduce the dose of glucocorticoid, improve significantly the long function indexes, and decrease the incidence of adverse reactions.关键词
哮喘/β2受体激动剂/糖皮质激素Key words
asthma/β2-adrenergic acceptor agonist/glucocorticoid分类
医药卫生引用本文复制引用
卢建新..糖皮质激素联合长效β2受体激动剂治疗轻中度哮喘的临床疗效[J].临床医学工程,2009,16(7):54-55,2.
