中国中西医结合杂志2001，Vol.21Issue(1)：54-57,4.
补肾活血中药对雌性幼龄大鼠乳腺发育作用及其机理的实验研究
Effect and Mechanism Study of Kidney Tonifying and Blood Circulation Activating Chinese Drugs on Development of Mammary Glands in Female Juvenile Rats
李培英 1欧阳惠卿2
作者信息
- 1. 广州中医药大学 广州 510407
- 2. 广州中医药大学第一附属医院
- 折叠
摘要
Abstract
Objective: To study the effect and mechanism of Kidney tonifyingand blood circulation activating Chinese drugs (KB) on development of mammary gland. Methods: Using the female juvenile rats as the experimental targets, the level of serum hormone, the amount and affinity of estradiol receptor (ER) and progesterone receptor (PR) as well as the DNA content and relative weight of the rats′ mammary glands were measured to study the effect of KB at the pre-receptor, receptor and post-receptor level. Results: KB markedly enhanced the serum level of estradiol, progesterone and the growth hormone (GH) at pre-receptor level, increased the number and affinity of estradiol and progesterone receptors both in the cytoplasm and nucleus at the receptor level. While at the level of post-receptor, it increased the DNA content and the weight index of mammary glands. Conclusion: The Kidney tonifying and blood circulation activating Chinese drugs are effective in promoting the growth and development of mammary glands.关键词
乳腺发育/补肾/活血/雌二醇/孕酮/雌二醇受体/孕酮受体分类
医药卫生引用本文复制引用
李培英,欧阳惠卿..补肾活血中药对雌性幼龄大鼠乳腺发育作用及其机理的实验研究[J].中国中西医结合杂志,2001,21(1):54-57,4.
