中德临床肿瘤学杂志（英文版）2007，Vol.6Issue(6)：546-548,3.
免疫功能对食管癌淋巴结微转移的影响
Effect of immune function on lymph node micrometastasis in esophageal cancer patients
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作者信息
- 1. Department of Thoracic Surgery of Henan Tumor Hospita1, Zhengzhou 450008, China;Department of Thoracic Surgery of Henan Tumor Hospita1, Zhengzhou 450008, China;Department of Thoracic Surgery of Henan Tumor Hospita1, Zhengzhou 450008, China
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摘要
Abstract
Objective: To explore the effect of immune function on lymph node micrometastasis in esophageal cancer patients by the research on the correlation between immune function and micrometastasis. Methods: Ratios of T-lymphocyte subsets CD3+, CD4+, CD8+ and CD4+/CD8+ in peripheral blood were examined by flow cytometry, but no lymph node with metastatic cancer cells was observed in middle thoracic esophageal squamous carcinoma patients by routine pathological examination.The patients were divided into 2 groups with or without micrometastasis to detect micrometastasis by immunohistochemical method, and T-lymphocyte subsets levels were compared between the 2 groups. Results: CD3+ and CD4+ T-lymphocytes levels of the group with micrometastasis were significantly lower than those of the group without micrometastasis, while CD8+level of the group with micrometastasis was significantly higher than that of the group without micrometastasis. Conclusion:T-lymphocyte subset is closely relative with micrometastasis, and prognosis of the patients with low CD3+ and CD4+ levels but high CD8+ T-lymphocytes is comparatively poor.关键词
esophageal cancer/ T-lymphocyte subset/ micrometastasisKey words
esophageal cancer/ T-lymphocyte subset/ micrometastasis分类
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..免疫功能对食管癌淋巴结微转移的影响[J].中德临床肿瘤学杂志（英文版）,2007,6(6):546-548,3.
