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结肠清颗粒对溃疡性结肠炎模型大鼠血清IL-1、ICAM-1含量的影响

范立昌 薛玲 王静 高鲁霞

中国当代医药2009,Vol.16Issue(12):5-6,2.
中国当代医药2009,Vol.16Issue(12):5-6,2.

结肠清颗粒对溃疡性结肠炎模型大鼠血清IL-1、ICAM-1含量的影响

Effects of Jiechangqing on IL-1 and ICAM-1 in the serum of Ulcerative Colitis Model Rats

范立昌 1薛玲 2王静 2高鲁霞2

作者信息

  • 1. 莒县人民医院药剂科,山东莒县,276500
  • 2. 山东中医药大学,山东济南,250355
  • 折叠

摘要

Abstract

Objective: To study the effects of Jiechangqing granule on the Ulcerative Colitis (UC) rats. Methods: To make the Ulcerative Colitis model rats by rabbit colon and Feud's adjuvant,and detected contents of IL-1 and ICAM-1 in the serum of the rats. Results: To compare with the model groups,the high-and mederate-dosage groups of Jiechangqing could up-regulated the contents of IL-1 and ICAM-1 and relieve the pathology changes significantly. Conclusion: Jiechangqing granule can up-regulated the levels of IL-1 and ICAM-1 contents in the serum of the rats ,which is the foundation to cure UC.

关键词

结肠清颗粒/溃疡性结肠炎/IL-1/ICAM-1

Key words

Jiangchangqing/Ulcerative colitis/IL-1/ICAM-1

分类

医药卫生

引用本文复制引用

范立昌,薛玲,王静,高鲁霞..结肠清颗粒对溃疡性结肠炎模型大鼠血清IL-1、ICAM-1含量的影响[J].中国当代医药,2009,16(12):5-6,2.

中国当代医药

1674-4721

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