中国临床康复2004，Vol.8Issue(3)：566-567,2.
化湿汤对中老年脾胃湿证腻苔患者血浆超氧化物歧化酶及丙二醛的影响
Effect of huashi decoction on plasm superoxide dismutase and malondialdehyde in patients with spleen-stomach damp syndrome
摘要
Abstract
AIM:To discuss the changes of plasm superoxide dismutase(SOD) and malondialdehyde(MDA) in patients with spleen-stomach damp syndrome with greasy fur and their effects in strengthening the spleen and removing dampness. METHODS:Plasm SOD and MDA of patients with white-greasy and yellow-greasy fur were detected using tube barbituric acid(TBA) and radioimmunoassay(RIA) methods,respectively;the effects of strengthening the spleen and removing dampness were observed. RESULTS:The levels of plasm SOD in patients with white and yellow greasy fur[(102.47± 11.03) μ mol/L and(104.68± 12.84) μ mol/L] were lower than those of thin-white fur in normal(121.95± 13.66) μ mol/L.The levels of plasm MDA increased obviously[yellow-greasy fur: (6.12± 0.72), (5.92± 0.67) μ mol/L;thin-white fur:( 4.28± 0.61) μ mol/L](t=3.12,2.87,P< 0.01).Both of them had parallel relation to the thickness of greasy fur.Huashi decoction could improve dampness and greasy fur,increase plasm SOD levels but decrease plasm MDA levels. CONCLUSION: Formation of greasy fur is related to free radical injury. The therapeutic mechanism of huashi decoction may be related to clearing oxygen-derived free radicals and preventing oxidative injury.关键词
脾胃湿热 /中医疗法/化湿/健脾/超氧化物歧化酶 /血液分类
医药卫生引用本文复制引用
金明华,秦鉴,丘瑞香..化湿汤对中老年脾胃湿证腻苔患者血浆超氧化物歧化酶及丙二醛的影响[J].中国临床康复,2004,8(3):566-567,2.基金项目
广东省中医药局基金资助项目(100113) （100113）
