中国神经再生研究(英文版)2008,Vol.3Issue(5):569-572,4.
Role of the hippocampus on learning and memory functioning and pain modulation
Role of the hippocampus on learning and memory functioning and pain modulation
Haimei Wang1
作者信息
- 1. Department of Pharmaceutical Sciences, Wuhan Bioengineering Institute, Wuhan 430415, Hubei Province, China
- 折叠
摘要
Abstract
The hippocampus, an important part of the limbic system, is considered to be an important region of the brain for learning and memory functioning. Recent studies have demonstrated that synaptic plasticity is thought to be the basis of learning and memory functioning. A series of studies report that similar synaptic plasticity also exists in the spinal cord in the conduction pathway of pain sensation, which may contribute to hyperalgesia, abnormal pain, and analgesia. The synaptic plasticity of learning and memory functioning and that of the pain conduction pathway have similar mechanisms, which are related to the N-methyl-D-aspartic acid receptor. The hippocampus also has a role in pain modulation. As pain signals can reach the hippocampus, the precise correlation between synaptic plasticity of the pain pathway and that of learning and memory functioning deserves further investigation. The role of the hippocampus in processing pain information requires to be identified.关键词
hippocampus/learning/memory/neuronal plasticity/painKey words
hippocampus/learning/memory/neuronal plasticity/pain分类
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Haimei Wang..Role of the hippocampus on learning and memory functioning and pain modulation[J].中国神经再生研究(英文版),2008,3(5):569-572,4.