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非发酵革兰阴性杆菌院内获得性肺炎调查及危险因素分析

李艳玲 王昆 苏新明 康健

中国现代医学杂志2004,Vol.14Issue(10):5-7,3.
中国现代医学杂志2004,Vol.14Issue(10):5-7,3.

非发酵革兰阴性杆菌院内获得性肺炎调查及危险因素分析

Nosocomical pneumonia by non-fermentation Gram negative bacilli:clinical investigation and risk factors analysis

李艳玲 1王昆 1苏新明 1康健1

作者信息

  • 1. 中国医科大学附属第一医院,呼吸疾病研究所,辽宁,沈阳,110001
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摘要

Abstract

Objective: To learn about the status quo of nosocomial pneumonia by non- fermentation Gram negative bacilli in the respiratory department in our hospital and give the clinical doctors some advicos when they choose the antibiotics to cure the infective diseases. Methods: Identified the bacilli with the rou-tine method and used the API system to identify them more; did drug-sensitive experiences with disk-diffuse method; and analyzed the clinical data in retrospect. Results: The separating rate of non- fermentation Gram negative bacilli was 62%, 35.8% of them was P.aeruginosa, 12.8% of them was Acinetobacter Baumannii,6.9% of them was Stenotrophomas maltophilia. 6.4% of them was B.cepacia. Clinical materials demonstrated that senile patients, critical undering disease as well as longation of duration in ICU, immunological dysfunc-tion, tracheal cannula and tracheotomy, broad-spectrum antibiotics use for a long time were the primary risk factors related to the nosocomial infection by non-fermentation Gram negative bacilli. Drug-sensitive experi-ments showed these bacteria had high resistance to cephalosporin and relative low resistance to compound of β lactamase inhibitor, imipenem, amikacin,ceftazidime and ciprofloxacin. Conclusions: Non- fermentation gram-negative bacilli are the major pathogens, they have high resistance rate and are difficult to control. To decrease the infection rate, we must prevent the infections systemically, reasonably use antibiotics and control high risk factors.

关键词

非发酵革兰阴性杆菌/医院获得性肺炎/危险因素

Key words

non-fermentation Gram negative bacilli/nosocomial pneumonia/risk factor

分类

医药卫生

引用本文复制引用

李艳玲,王昆,苏新明,康健..非发酵革兰阴性杆菌院内获得性肺炎调查及危险因素分析[J].中国现代医学杂志,2004,14(10):5-7,3.

中国现代医学杂志

OA北大核心CSTPCD

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