高等学校化学学报2001，Vol.22Issue(4)：573-576,4.
雷公藤内酯甲的制备和晶体结构
Crystal Structure and Preparation of Wilforlide A
李良学 1刘继德 1尹业高 1谌了容 2苏洪英2
作者信息
- 1. 荆州师范学院化学系,
- 2. 武汉大学化学与环境科学系,
- 折叠
摘要
Abstract
A pure wilforlide A was separated from the ethanolic extract of tripterygium wilfordii Hook. F. root. The compound was characterized by IR, 1H NMR and microanalysis. Its crystal structure was also determined by X-ray crystallography. The title compound is formulated as C30H46O3 with formulae weight Mr=454.70. Its crystal belongs to orthorhombic system with P212121 space group. The crystal cell parameters are a=0.732(4) nm, b=1.283(7) nm, c=2.693(6) nm; V=2.532 7 nm3, Z=4, Dc=1.192 g*cm-3, μ(Mo Kα)=0.695 cm-1, F(000)=1 107. The final R=0.039, RW=0.044. The title compound is a five-membered ring terpene, whole skeleton of molecule stretches folded. The results of AM1 calculation shows that the molecule is polar and reactive to the nucleophilic and redox reactions.关键词
雷公藤内酯甲/制备/晶体结构/活性分类
化学化工引用本文复制引用
李良学,刘继德,尹业高,谌了容,苏洪英..雷公藤内酯甲的制备和晶体结构[J].高等学校化学学报,2001,22(4):573-576,4.
