高等学校化学学报2001，Vol.22Issue(4)：577-580,4.
人纤维蛋白溶酶原的化学修饰
Chemical Modification of Human Plasminogen
梁放 1吴一卉 1曹海石 1郭慧云 1刘兰英 1孙宏 2陈维金 2刘淑英2
作者信息
- 1. 吉林大学生命科学学院,
- 2. 长春生物制品研究所,
- 折叠
摘要
Abstract
The chemical modification of human plasminogen(HPg) was studied with NAI, 1,2-cyclohexanodine, Ch-T, and EDC as the modification reagents on its Tyr, Arg, Met and carboxyl groups. The results indicate that Tyr and Arg residues are not activity dependent groups, while Met and carboxyl groups played an important role on HPgs activity. The kinetic analysis demonstrates that one Met residue and two carboxyl groups are essential for HPgs activity.关键词
人纤维蛋白溶酶原/化学修饰/羧基/蛋氨酸分类
生物科学引用本文复制引用
梁放,吴一卉,曹海石,郭慧云,刘兰英,孙宏,陈维金,刘淑英..人纤维蛋白溶酶原的化学修饰[J].高等学校化学学报,2001,22(4):577-580,4.
