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复方中药对人宫颈癌Hela细胞生长和凋亡的影响

谭忠伟 江振友 岳磊 邹林 施珊珊 肖京中

国际医药卫生导报2009,Vol.15Issue(9):5-8,4.
国际医药卫生导报2009,Vol.15Issue(9):5-8,4.DOI:10.3760/cma.j.issn.1007-1245.2009.09.001

复方中药对人宫颈癌Hela细胞生长和凋亡的影响

Effects of complex prescription of traditional Chinese medicine on the growth of HeLa cells in Vitro

谭忠伟 1江振友 2岳磊 2邹林 2施珊珊 2肖京中3

作者信息

  • 1. 529000,江门市妇幼保健院检验科
  • 2. 510632,暨南大学医学院,微生物学与免疫学教研室
  • 3. 510000,广州葆盛科技开发有限公司
  • 折叠

摘要

Abstract

Objective To investigate the influence of the traditional Chinese medicine extract (Baosheng Oral Liquid) on the growth of human cell line Hela in vitro and its probable mechanism, Methods The inhibition of Baosheng Oral Liquid on Hela cells and human normal liver line 7701 cells proliferation was detected by MTT method, cell apoptosis and expression of apoptosis gene fas were further analyzed with flow cytometry in which anti-tumor drug Cisplatin was employed as control. Results Baosheng Oral Liquid remarkably inhibited the growth of Hela cells. Flow cytometric analysis showed that apoptosis of the tumor cells was induced and expression of Fas was enhanced. Conclusion apoptosis may play an important role in the anti-tumor effect of Baosheng Oral Liquid.

关键词

复方中药/细胞凋亡/Fas基因

Key words

Chinese complex prescription/ Apoptosis/ Fas gene

分类

医药卫生

引用本文复制引用

谭忠伟,江振友,岳磊,邹林,施珊珊,肖京中..复方中药对人宫颈癌Hela细胞生长和凋亡的影响[J].国际医药卫生导报,2009,15(9):5-8,4.

基金项目

广东省科技计划项目课题(NO:83057),广东省中医药局建设中医药强省科研课题(NO.1060117) (NO:83057)

国际医药卫生导报

1007-1245

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