兰州大学学报（医学版）2009，Vol.35Issue(2)：58-59,63,3.
血清心肌肌钙蛋白Ⅰ与肌酸激酶同工酶-MB在小儿病毒性心肌炎诊断中的应用
Application of the combination tests of serum cardiac troponin Ⅰ and creatine kinase-MB in diagnosis of children patients with viral myocarditis
张建轩 1康晓东 2朱世武1
作者信息
- 1. 兰州石油化工公司总医院检验科
- 2. 兰州石油化工公司总医院儿科,甘肃,兰州,730060
- 折叠
摘要
Abstract
Objective To study the clinical value of serum cardiac troponin Ⅰ (cTnⅠ) and creatine kinase-MB (CK-MB) in the diagnosis of children with viral myocarditis. Methods The methods of enhanced immune turbidimetry and enzyme rate were used to test the positive rate of cTnⅠ and CK-MB in the serum of 59 children with viral myocarditis,41 children without viral myocarditis and 41 healthy children. Results The contrast of the positive rate of cTnⅠ and CK-MB in the serum among the three groups showed the significant differences (χ2=72.21,P <0.05; χ2=35.24, P<0.05). The positive rate of CK-MB was lower than that of cTnⅠ in children with viral myocarditis (χ2=4.32,P <0.05). The positive rate of cTnI was lower than that of CK-MB in children without viral myocarditis (χ2= 21.09,P <0.05). The positive rate of cTnⅠ and CK-MB in the serum of healthy children was the same 0. The positive rate of CK-MB in serum was decreasing along with the prolonged course of disease. When the course of disease was within one week,the positive rate of cTnI in serum was higher than that of CK-MB (χ2=4.50,P<0.05). Conclusion The cTnⅠ in serum has high sensitivity and specificity to diagnose children with viral myocarditis. Thus it can be used as the reliable indicator for the early diagnosis of the children patients with viral myocarditis.关键词
病毒性心肌炎/心肌肌钙蛋白Ⅰ/肌酸激酶同工酶-MB/儿童Key words
viral myocarditis/cardiac troponin Ⅰ/creatine kinase-MB/child分类
医药卫生引用本文复制引用
张建轩,康晓东,朱世武..血清心肌肌钙蛋白Ⅰ与肌酸激酶同工酶-MB在小儿病毒性心肌炎诊断中的应用[J].兰州大学学报（医学版）,2009,35(2):58-59,63,3.
