中德临床肿瘤学杂志(英文版)2008，Vol.7Issue(10)：590-592,3.
骨转移前列腺癌的临床诊治研究报道
Clinical features and management of prostate cancer with bone metastases: the first report of our Institute
Zhijian Shen 1Honglin Xie 2Chaojun Wang 1Songliang Cai 1Liping Xie 1Suo Wang 1Zhigen Zhang1
作者信息
- 1. Department of Urology, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310003, China
- 2. Department of Urology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou 310013, China
- 折叠
摘要
Abstract
Objective: To summarize the experience of diagnosis and treatment outcomes for bone metastatic prostate cancer. Methods: A retrospective study with a total of 128 prostate cancer (Pca) was performed from 2000 to 2005, in our institute. We analyzed the clinical features and outcomes of patients with bone metastases and the data and follow-up of 63 bone metastases was collected by one registrar. Cochran Armitage trend test was used for statistic analysis and a P-value of < 0.05 was taken as statistically significant. Results: The mean age was 73 (range 55 to 87) years. The PSA level was from 0.083 ng/mL to 6462 ng/mL. Bone metastases morbidity had good relationship with PSA level. With the mean follow up of 30 (range 6 to 72) months for 52/63 (82.5%) patients, 15 (28.8%) died from Pea with a mean survival of 21 months and 1 patient with PSA less than 4 ng/mL at the time died from cerebrovascular suddenness 6 months post-treatment. Conclusion: The early effect of endocrine treatment for bone metastases is obvious, and palliative prostatectomy is satisfactory and able to improve the quality of life rapidly for patients with obstructive symptoms.关键词
prostate cancer (Pca)/bone metastases/prostate specific antigen (PSA)Key words
prostate cancer (Pca)/bone metastases/prostate specific antigen (PSA)分类
临床医学引用本文复制引用
Zhijian Shen,Honglin Xie,Chaojun Wang,Songliang Cai,Liping Xie,Suo Wang,Zhigen Zhang..骨转移前列腺癌的临床诊治研究报道[J].中德临床肿瘤学杂志(英文版),2008,7(10):590-592,3.
