四川大学学报（医学版）2008，Vol.39Issue(4)：595-600,6.
中国汉族青年低脂高糖膳食6天后的血清高密度脂蛋白、胆固醇水平
No Decrease of HDL Cholesterol after 6 Days of Low Fat and High Carbohydrate Diets in a Young Chinese Han Pop-ulation
李正科 1汤慧 1龚仁蓉 2林佳 1甘禅芬 1黄鑫 1李蓉辉 1方定志1
作者信息
- 1. 四川大学华西基础医学与法医学院生物化学与分子生物学教研室,成都,610041
- 2. 四川大学华西医院心胸外科
- 折叠
摘要
Abstract
More studies are needed on the hyperyriacylglycerolemic effects of low fat and high carbohydrate (LF-HC) diet in young population, especially Chinese who generally have a diet containing lower fat and higher carbohydrate. To test them in a young Chinese Han population, 56 healthy subjects (22.89±1.80) years were given regular diet of 31% fat and 54% carbohy-drate for 7 days, followed by LF-HC diet of 15% fat and 70% carbohydrate for 6 days, without total energy restriction. After the LF-HC diet, the male experienced an increase of high density lipoprutein (HDL) cholesterol and decreases of weight, body mass index (BMI), total cholesterol (TC), and LDL (low density lipoprotein) cholesterol (P < 0.05). The female experienced in-creased serum triacylglycerol and insulin, and decreased TC and LDL cholesterol (P < 0.05). When BMI was taken into account,all the subjects with low, medium, or high BMI experienced decreases of TC and LDL cholesterol although some changes were not significant. No significant decrease of HDL cholesterol was found, while significantly increased HDL cholesterol and apolipoprotein A-Ⅰ (apo A- Ⅰ) were found in the male subjects with low or high BMI (P < 0.05). Significant increase of triacylglycerol was observed only in the female subjects with low or medium BMI. In conclusion, subjects with different BMI and gender have different triacylglycerol and HDL cholesterol responses to LF-HC diets, and significant increase of HDL cholesterol and apolipoprotein A- Ⅰ were observed in some young male subjects.关键词
低脂高糖膳食/高密度脂蛋白胆固醇/甘油三酯/性别/体重指数Key words
Low fat and high carbohydrate diets HDL cholesterol Triacylglycerol Gender Body mass index分类
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李正科,汤慧,龚仁蓉,林佳,甘禅芬,黄鑫,李蓉辉,方定志..中国汉族青年低脂高糖膳食6天后的血清高密度脂蛋白、胆固醇水平[J].四川大学学报（医学版）,2008,39(4):595-600,6.
