中国临床康复2004，Vol.8Issue(27)：5977-5979,3.
复方壳多糖对生长期大鼠体质量和血脂水平的影响
Effect of compound chitosan on body mass and blood lipid level of rats in growing period
罗萍 1张纯洁 1冯驰 1陈大义1
作者信息
- 1. 四川省卫生管理干部学院检验系,四川省成都市,610041
- 折叠
摘要
Abstract
BACKGROUND:Experimental and clinical studies have demonstrated that chitosan can reduce body mass and blood lipid level.However,it induces some side effects due to large doses. OBJECTIVE:To explore the effect of compound chitosan on body mass and blood lipid level of rats in growing period. DESIGN:Completely randomized grouping experiment. SETTING AND PARTICIPANTS:A total of 80 healthy SD rats(SPF degree),aged 3- 4 weeks old,were divided into 4 groups and fed in the animal room with constant temperature with barrier system in Sichuan Continuing Education College of Medical Sciences.All experimental indexes were measured in the laboratory of our college. INTERVENTIONS:Group A was normal control group and treated with essential diet;Group B was high lipid control group and treated with high lipid diet;Group C was chitosan group and fed with chitosan diet;Group D was compound chitosan group and treated with compound chitosan diet. MAIN OUTCOME MEASURES:Growth and development indexes like body mass and blood serum lipid of the rats four weeks after feeding. CONCLUSION:A certain amount of chitosan intake has no effect on the growth of rats in growing period,and it can lower serum TG level.Compound chitosan has greater effects of both reducing serum lipids and body mass and raising HDL-C level than chitosan alone.关键词
大鼠/壳多糖/中药(复方)/体重/高脂血症分类
医药卫生引用本文复制引用
罗萍,张纯洁,冯驰,陈大义..复方壳多糖对生长期大鼠体质量和血脂水平的影响[J].中国临床康复,2004,8(27):5977-5979,3.
