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Axial intensity in a fiber-optic confocal microscope

LIU Yong CHEN Jia-bi REN Qiu-shi WANG Cheng LI Wan-rong

光学精密工程2005,Vol.13Issue(5):608-612,5.
光学精密工程2005,Vol.13Issue(5):608-612,5.

Axial intensity in a fiber-optic confocal microscope

Axial intensity in a fiber-optic confocal microscope

LIU Yong 1CHEN Jia-bi 2REN Qiu-shi 1WANG Cheng 2LI Wan-rong2

作者信息

  • 1. Optical and Electronic Information Engineering College,University of Shanghai for Science & Technology,Shanghai 200093,China
  • 2. Institute for Laser Medicine & Bio-photonics,Shanghai Jiaotong University, Shanghai 200030,China
  • 折叠

摘要

Abstract

A fiber-optic confocal microscope has been analyzed by Fourier optics.It is found that the detected light intensity has three parts,each of which is depennted on the coupled lens,the detective lens,and the part comprised of the fiber and the microprobe.The simulated results show that the less the value of the parameter A is,which is dependent on the fiber and microprobe,the higher the axial resolution of the system is. For the case,as A→∞, the axial resolution is zero,which is corresponding to the conventional microscope.as A≤1,the axial resolution changes slightly,and is close to the optimal value,which is corresponding to the perfect confocal microscope.when the reflective loss takes place at the end of fiber,the contrast of axial intensity will decrease.All that will help the design of endoscope with confocal microscope at cellular level.

关键词

confocal microscope/point spread function(PSF)/single-mode fiber/object function/axial intensity

Key words

confocal microscope/point spread function(PSF)/single-mode fiber/object function/axial intensity

分类

数理科学

引用本文复制引用

LIU Yong,CHEN Jia-bi,REN Qiu-shi,WANG Cheng,LI Wan-rong..Axial intensity in a fiber-optic confocal microscope[J].光学精密工程,2005,13(5):608-612,5.

基金项目

National natural science foundation of China(No.60371021) (No.60371021)

光学精密工程

OA北大核心CSCD

1004-924X

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